AstraZeneca today confirmed that it is in talks with Acerta Pharma to acquire the company in a potential deal worth $5 billion.In a statement, AstraZeneca said it is “exploring potential strategic options” with Acerta.
On Friday, the Wall Street Journal reported that AstraZeneca was interested in Acerta and, in particular, its cancer drug acalabrutinib.
Acalabrutinib, also known as ACP-196, is a novel, orally bioavailable, second-generation, irreversible inhibitor of Bruton’s tyrosine kinase (Btk) that was rationally designed to be more potent and selective than existing Btk inhibitors. Acerta is currently developing acalabrutinib in multiple hematologic malignancies and solid tumors, as well as rheumatoid arthritis.

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